Videos

Guiding Selection and Design in Hit-to-Lead

Oct 16, 2013

Guiding Selection and Design in Hit-to-Lead

Oct 16, 2013

The objective in this example is to identify one or more high quality chemistries for progression to detailed in vitro and in vivo studies, based on initial screening data for potency; ideally the compounds chosen for progression should not only be potent, but also have appropriate ADME properties to result in a high quality lead series. We will also use StarDrop to explore potential modification of one of the existing compounds to improve its properties.

To try this example yourself, please visit the Tutorials section of the Community. If you don’t have access to StarDrop or the optional modules and would like to arrange a free trial license, please email us at info@optibrium.com

To hear the narration, please increase your speaker volume.