Tutorials

R-Group Analysis

Oct 16, 2013

R-Group Analysis

Oct 16, 2013

In this example we look at R-Group analysis of chemical series to identify key functionalities which influence potency. One example looks at a series of analogues of Buspirone and a second uses a multi-scaffold R-group analysis to analyse SAR across two scaffolds with equivalent substitution points.

To try this example yourself, download the example project file and follow the step-by-step guidelines in this PDF.

Please note that the tutorial explores core features of StarDrop. If you don’t have access to StarDrop and would like to arrange a free trial license, please email us at info@optibrium.com

You can also watch a video of this tutorial here, others that might interest you can be found in the tutorials section of our video archive.

Please note that this video was recorded with an earlier version of StarDrop, so there may be small differences in appearance, however the process demonstrated is unchanged.