StarDrop Plug-in Modules
Select from a range of optional plug-in modules
StarDrop's core features can be extended with a comprehensive range of optional plug-in modules; predictive models for ADME properties; P450 metabolism and toxicity; automatic QSAR model building; 3D SAR analysis; and de novo design to stimulate the search for new optimisation strategies.

ADME QSARHigh quality predictive QSAR models of key ADME propertiesBefore committing resources to in vivo and in vitro studies, it's vital to know you're working with the best molecules. StarDrop is built to help you predict a wide range of ADME and physiochemical properties in silico, allowing you to explore all of your options and giving you confidence in your decisions. |
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Auto-ModellerBuild and validate robust QSAR models tailored to your chemistry and dataThis module gives novice and expert users alike access to the tools needed to produce validated, predictive models. Output from the Auto-Modeller includes Glowing Molecule results that help to visualise the structure-activity relationships captured from your chemistry and data. |
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NovaGenerate and prioritise new, relevant compound ideasGenerate and prioritise new compounds ideas to stimulate the search for compound optimisation strategies for your project:
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BIOSTERA world of chemistry experienceAn optional extension to the Nova modules, providing over 27,000 structure modifications and replacement techniques that have been used in analogue design:
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P450Predict metabolic routes, sites, products and labilityUsing StarDrop's P450 metabolism models you can quickly identify the regions of your compounds that are most vulnerable to metabolism by the major drug metabolising isoforms of cytochrome P450 and predict the metabolites formed. |
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Derek NexusKnowledge-based prediction of over 40 toxicity endpointsStarDrop's Derek Nexus module provides Lhasa Limited's world-leading technology for knowledge-based prediction of key toxicities, helping to guide the design of safe and efficacious drugs in hit-to-lead and lead-optimisation. |
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torch3DUnderstand and apply 3D ligand-based SAR to identify and optimise novel activesStarDrop's torch3D module, using Cresset's molecular Field technology, provides a unique, 3-dimensional (3D) insight into the biological activity, properties and interactions of your compounds, helping to guide the design of novel, potent compounds with a high chance of success. |
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SeeSAR3D Structure-based designSeeSAR, developed in collaboration with BioSolveIT, is a suite of three modules which seamlessly interact to enable you to easily visualise ligand and protein structures, identify key interactions driving binding affinity and link the design of new compounds in two and three dimensions. |
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MPO ExplorerDevelop multi-parameter optimisation strategiesThis module provides novel, patented methods to guide 'strategic' decisions for your discovery projects.
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