Scaffold Hopping with Library Enumeration

Wednesday, 29 January 2014 00:00
Edmund Champness

In this example we are going to use the library enumeration feature in StarDrop’s Nova module, in combination with R-group analysis, to generate a virtual library representing a potential new lead series. This will be based on a previous series and explore the impact of a change of scaffold and variations in a side chain, while retaining the substituents at two key positions.

To try this example yourself, please visit the Tutorials section of the Community. If you don't have access to StarDrop or the optional modules and would like to arrange a free trial license, please email us at

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Last Updated on Thursday, 11 January 2018 16:04