The GalaXi® Search Tool is an add-on to StarDrop which searches the WuXi GalaXi® space for compounds that are similar to a query structure of interest. WuXi's GalaXi® is a chemical space that contains billions of virtual compounds, largely built from WuXi AppTec’s library of novel drug-like scaffolds. Due to a carefully selected building block supply and proven chemistry, the GalaXi® space consists of molecules that can be quickly synthesized on demand. Once you’ve identified compounds of interest, you can easily send the required information to WuXi to request a quote, directly from StarDrop. This tool is analogous to searching the GalaXi® space using BioSolveIT’s InfiniSee software and uses their FTrees technology to quickly search the enormous chemical space. You can find more information on FTrees at www.biosolveit.de/FTrees/.
This script provides an extension to StarDrop that enables you to search GalaXi® directly from StarDrop, returning the data pre-formatted and ready to analyse within StarDrop. For example, you can use this to
- Investigate the chemical space local to your compound
- Find structurally novel leads with improved properties or avoid patent-protected space