Matched Series Analysis

Matched Series Analysis

Matched Series Analysis The objective in this worked example is to identify new derivatives that are likely to improve activity at their target, given the SAR already generated on a project. To try this example yourself, download the data file and follow the...
Inspyra

Inspyra

Inspyra This worked example uses Inspyra™ to interactively explore optimisation strategies to achieve a selective inhibitor of DPP-4 with appropriate physicochemical properties. Starting from a data set of compounds representing three chemical series based on...
Inspyra Matched Series Analysis

Inspyra Matched Series Analysis

In this worked example, we will explore ways to use the Inspyra Panel, in combination with Matched Series Analysis (MSA). MSA goes beyond Matched Pair Analysis and uses longer series of matched compounds to propose new substitutions that are likely to improve activity...