StarDrop Case Studies

What StarDrop is capable of

The following case studies demonstrate examples of what StarDrop is capable of. If you’d like to know more or arrange an on-site demonstration, contact us for more details.

StarDrop Case Studies

Drug Constellations

Optibrium’s drug constellations provide an instant, visual summary of important small-molecule drugs for a therapeutic class or indication. 

User-friendly database querying

Seamless connectivity between design and decision making tools and the data management system ensures that project teams have access to the latest information without needing to compile the data manually from many sources.

Balancing properties in lead optimisation

Parallel optimisation is essential to developing compounds with the correct balance of properties. In this study, we identified four compounds that had been overlooked by traditional compound selection based on selectivity and potency cut-off values. 

In silico Guided Hit-to-Candidate

A key principle in the efficient progression of compounds from Hit to Candidate is effective decision making. 

Fast Follower - Improving Metabolic Stability

This project’s goal was to employ a ‘fast-follower’ strategy to improve on a competitor compound that had problems with poor oral bioavailability and short and variable half-life in man. 

Rapid Focus in Lead Optimisation

The application of StarDrop to this project could have resulted in a 90% saving in compounds synthesised. 

INTERESTED?

Try StarDrop

With its comprehensive suite of integrated software, StarDrop™ delivers best-in-class in silico technologies within a highly visual and user-friendly interface. StarDrop™ enables a seamless flow from the latest data through predictive modelling to decision-making regarding the next round of synthesis and research, improving the speed, efficiency, and productivity of the discovery process.

Other StarDrop™ Modules