by Marina Chenery | Nov 26, 2013 | Presentations and Webinars, Videos
Fragment-based screening, what can we learn from published hits? This talk was given by Dr Chris Swain, Cambridge MedCem Consulting, at Optibrium’s Drug Discovery Consultants’ Day – November 2013. A copy of Chris’ slides can be downloaded here....
by Marina Chenery | Nov 21, 2013 | Multi-Parameter Optimisation, Publications and presentations
Summary In this drug optimisation article, coauthored with Pfizer we discuss new ‘rule induction’ methods. These explore complex data to find interpretable, multi-parameter rules, tailored to any drug discovery objective, and are useful in identifying...
by Marina Chenery | Nov 1, 2013 | Drug Discovery Applications, Publications and presentations
Summary In this article, ‘Addressing toxicity risk when designing and selecting compounds in early drug discovery’, we discuss the application of expert knowledge-based predictions of toxicity. We highlight how they can be used with multi-parameter...