by Marina Chenery | Oct 29, 2010 | General, Publications and presentations
Summary This article discusses a critical issue that the community needs to address address in order to use the predictive models that we build to the greatest effect. To understand how useful predictive models are in a practical context, we need to understand...
by Marina Chenery | Oct 7, 2010 | Drug Discovery Applications, Metabolism, Publications and presentations
Poster: Guiding Focused Design of Potent Leads with Improved Metabolic Stability Matt presented this poster at ISSX in September 2010. Abstract: A number of methods have been developed for the prediction of regioselectivity of metabolism by the major drug metabolising...
by Marina Chenery | Oct 7, 2010 | In Silico Modelling, Metabolism, Publications and presentations
Poster: Predicting Regioselectivity and Lability of Cytochrome P450 Matt presented this poster at ISSX in October 2011. Abstract: Many computational methods have been developed that predict the regioselectivity of metabolism by drug metabolising isoforms of the...
by Marina Chenery | Oct 7, 2010 | In Silico Modelling, Publications and presentations
Poster: Automatic Generation and Validation of QSAR Toxicity Models Matt presented this poster at ISSX in October 2011. Abstract: Whether compounds are intended as drugs, cosmetics, agrochemicals or for other industrial application, it is essential to understand their...