 | A new generation of possibilities - Rigorously explore the chemistry around hits - Discover lead-hopping opportunities - Generate new strategies to overcome liabilities - Identify patent-busting possibilities |
New ideas, broader horizons
Nova helps you generate new compound ideas, expand your searches, develop new chemistry strategies and find ways around patents by opening up a world of opportunities in the hunt for those elusive, high-quality compounds you may have overlooked or simply not thought of.
Variations on a theme
Nova exponentially broadens your search by taking a 'parent' molecule and creating new generations of related compounds. Using a built-in collection of typical 'medicinal chemistry' transformations, Nova explores generations of potential 'children'. Nova provides an initial library of over 200 transformations for you to apply. Furthermore, using Nova you can apply multiple generations of transformations and bias selection in favour of a property or score.
New and useful compounds
Generating more choice isn't good in itself - especially if the additional choice isn't realistic. Nova creates compounds that 'make sense' from a medicinal chemistry perspective: because its transformation rules are derived from medicinal chemistry experience. Nova generates not only functional group replacements but can also make framework modifications. You can then quickly determine which ideas to focus on using StarDrop's probabilisitc scoring, chemical space, Glowing Molecule and other data visualisation.
A step-change in your thinking
Nova works like a team of experts. With Nova you can apply the cumulative knowledge and expertise of many medicinal chemists to compliment your thinking. By offering a completely different dimension to your research, Nova acts as a vastly experienced and creative addition to your team. Storing and applying many more transformations than a single chemist, it boosts your potential to find an optimal compound.
A flexible management tool
Nova takes full advantage of your expertise by allowing you to add and apply your own transformations, transferring your knowledge to other members of the team. It is also acts as a useful repository for knowledge, as transformations sets can be shared and 'favourites' flagged.
