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New Mitsubishi-Tanabe application note
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New Mitsubishi-Tanabe application note
nick foster
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Structural development of a hA2AAr antagonist considering ADME profiles

We are delighted to announce that the winner of our Application note competition is Dr Okamoto Masako from the Mitsubishi Tanabe Pharma Corporation. Her application note examines hA2AAr as a drug target as hA2AAr antagonists can potentially be developed for the treatment of neurodegenerative disorders such as Parkinson's disease. A number of hA2AAr antagonists have recently been reported by research groups, and with the availability of X-ray crystal structures it is now possible to better understand their SAR. Hence, this report explores the possibility of developing the strucuture of a known hA2AAr antagonist by considering ADME Scoring Profiles using StarDrop. Read more about this work from Dr Okamoto Masako at Mitsubishi Tanabe Pharma Corporation...
 
Last Edit: 2013/01/08 07:51 By nick foster.
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